Oncotype DX® Colon Recurrence Score

52-Year-Old Female Patient

with Stage III A/B (N1-3) tumor

Patient Details

Stage III A/B (N1-3)
Low (1)

Other Information:

Lymph node status was negative, but extra nodal tumor deposits: N1c

Patient received two does of 5-FU Oxaliplatin, but Oxaliplatin was stopped when the patient showed neuropathy and other signs of intolerable toxicity. The patient is continuing with capecitabine only.

Clinical Experience

Prognosis for Stage III A/B Colon Cancer Patients Following Adjuvant Chemotherapy

The clinical validation study included patients from the NSAPB C-07 trial which randomized 409 stage III A/B patients to 5FU/LV versus 5FU/LV+oxaliplatin.1

The average 5 year risk of recurrence for patients who had a Recurrence Score® result of 0 was:

Colon Cancer Stage III A/B Recurrence Score

Other Considerations: The recurrence risk for patients with ≥ 12 nodes examined was lower than the risk for those with < 12 nodes examined.


1. Yothers et al. J Clin Oncol. 2013.

Disclaimer: These case studies are brought to you for educational purposes only and should not be interpreted as an endorsement of Exact Sciences or its services by the submitting physician, or any other product or therapy. The information is sometimes related to interpretive diagnostic opinions of the treating physicians, and is not intended to represent the “standard of care.” The case studies reflect real life cases of patients who have used Oncotype DX, however they are individual results and results do vary. The examples are not necessarily representative of all of those who will use our clinical tests. Exact Sciences does not endorse any of the contributors featured on this site.

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Recurrence Score®0