Oncotype DX® Breast DCIS Score

50 Year-Old Female Patient

with 0.3 cm tumor

Patient Details

0.3 cm
ER positive
Not Provided
Not Provided
Not Provided
Not Provided
Positive ≥ 6.5
Positive ≥ 5.5

Other Information:

Treated with lumpectomy and tamoxifen


Clinical Experience


The Clinical Validation study1 included female patients with DCIS treated with local excision without irradiation, and required clear surgical margins ≥3 mm and a lesion size of ≤2.5 cm. Approximately a third of patients were treated with tamoxifen. The average 10 year rate for ipsilateral breast events for patients who had a DCIS Score of 12 was:


Quantitative hormone receptor analysis

The Oncotype DX test uses RT-PCR to determine the RNA expression of the genes below. These results may differ from ER or PR results reported using other methods or reported by other laboratories.

ER Score8.7
PR Score7.4


1. Solin et al. J Natl Cancer Inst. 2014.
2. Rakovitch et al. Breast Cancer Res Treat. 2015.
3. Rakovitch et al. ASCO. 2017.

Disclaimer: These case studies are brought to you for educational purposes only and should not be interpreted as an endorsement of Exact Sciences or its services by the submitting physician, or any other product or therapy. The information is sometimes related to interpretive diagnostic opinions of the treating physicians, and is not intended to represent the “standard of care.” The case studies reflect real life cases of patients who have used Oncotype DX, however they are individual results and results do vary. The examples are not necessarily representative of all of those who will use our clinical tests. Exact Sciences does not endorse any of the contributors featured on this site.

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ER Score8.7
PR Score7.4